AMD supported Amuse AI software goes open source, works with all GPU vendors - harlan4096 - 11 December 25
Quote:AMD’s sponsored Amuse AI software is now open source
![[Image: AMD-AMUSE-AI-HERO-1200x624.jpg]](https://cdn.videocardz.com/1/2025/12/AMD-AMUSE-AI-HERO-1200x624.jpg)
Amuse AI just went open source on GitHub, but it is not actually an AMD-made app. It is built by TensorStack AI, a small startup that works with AMD as a software partner and gets promoted on AMD’s site as a recommended front end for Ryzen AI and Radeon hardware. The GitHub repo calls this the “final version”, so this looks more like a curtain call than the start of a new development cycle.
The app itself is a Windows .NET program that runs on ONNX. No Python, no virtual envs. It can talk to AMD, NVIDIA and Intel GPUs, plus iGPUs and CPUs, by switching ONNX backends like DirectML or CUDA. Inside the UI you can grab a big list of Stable Diffusion style models with one click and do basic text to image, image to image and some simple video stuff.
![[Image: AMD-AMUSE-850x328.png]](https://cdn.videocardz.com/1/2025/12/AMD-AMUSE-850x328.png)
Source: Amuse AI
Amuse AI does not keep pace with the latest diffusion models or tricks and it is not as fast or flexible as a good ROCm plus ComfyUI setup on newer Radeon cards. People on Reddit also point out that ComfyUI is much more capable but feels like a developer tool, with graphs, plugins and the usual Python dependency headaches that can scare off casual users.
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